Parkinson’s Disease

Parkinson’s Disease

Study-related travel may be provided at no cost to many study participants and their study partner including flights, ground transportation, lodging, and meals for both the patient and caregiver. Travel arrangements and reimbursements may vary from study to study.

The Rocky Mountain Movement Disorders Center is currently conducting a large number of clinical trials for the treatment of Parkinson’s disease. We are conducting studies ranging from phase I to phase 4 including evaluating treatments that have potential to slow the progression of Parkinson’s Disease as well as evaluating in number of innovative new treatments to improve symptoms in patients with early, mid-stage, and advanced Parkinson’s disease. Many of the studies are sponsored by the National Institutes of Health while other studies involve evaluating the effect of new medications developed by the pharmaceutical industry.


Learn about surgical treatment options for Parkinson’s disease, focusing on deep brain stimulation. We discuss indications for surgery, methodology, target sites, hardware, programming, risks, benefits, limitations and typical results. It is important to consider clinical trials prior to Deep Brain Stimulation because once you have had DBS you no longer qualify for most studies and the procedure is irreversible.


At the Rocky Mountain Movement Disorders Center we take a comprehensive approach to achieve your well being. We provide all proven, effective and promising available treatments options such as prescribing a health diet & exercise, correctly administering proven medications, deep brain stimulation, as well offering patients opportunities to take part in clinical trials which at times is the most appropriate course of action. We have a full set of tools in our tool box. If you go to a DBS specialist, they are most likely going to advise brain surgery. When you are a hammer, everything looks like a nail. Come to the Rocky Mountain Movement Disorders Center, where we have a comprehensive approach to your care and weigh all the options carefully in consideration of what is best for you.

Deep Brain Stimulation Education


Surgical treatment for Parkinson’s disease is indicated for patients who have disabling motor complications despite maximal drug therapy. This includes disabling levodopa-induced dyskinesias, medication-refractory disabling tremor or marked motor fluctuations in which there is variation in mobility from extremely immobile to good functioning. Surgical treatment is very helpful to treat motor complications, but with the exception of improving tremor does not significantly improve the patient’s best response to levodopa. Effectively, surgery allows patients to function as they do during their best peak time on levodopa, with significant reduction in dyskinesia and marked reduction in motor fluctuations.


Preoperative response to levodopa is the best indicator of a patient’s response to surgical treatment. In general, patients who are good candidates for surgery have had Parkinson’s disease for five to ten years or more and have significant disability as a result of motor fluctuations, dyskinesias, or disabling tremor. They should not have significant cognitive impairment or dementia since surgery may, in fact, worsen this problem. Because of the risks of surgery, there should be a reasonable expectation of several years of life expectancy following surgery for the risk-benefit ratio to be reasonable. Even elderly patients who are in good general health and are cognitively well may be considered for surgery if they otherwise fulfill the criteria.



Space in this study is limited.
To be considered, please fill out the form or call 720-776-0092.


No cost studies are currently available for qualified participants.


No health insurance required


Compensation for time and travel TBD



Male / Female



701 E Hampden Ave, Ste 510
Englewood, CO 80113

State-of-the-Art Facilities

CenExel RMCR is Colorado's premier clinical research organization. For over 15 years, we’ve helped improve the quality of life for everyone by researching new medications and treatments. Our state-of-the-art facility is held to the highest standards of cleanliness and quality.

Board-Certified Physician

Your safety is our greatest concern. Every study at CenExel RMCR is overseen by expert medical staff and one of the most well-respected, board-certified physicians in the clinical research industry with 25+ years of experience.

FDA-Approved Procedures

Rest assured, you are not signing up for treatment with “experimental” methods. RMCR only uses FDA approved methods as if you were at any other hospital or clinic. Our research is focused on the medication associated with those methods.

Frequently asked questions

What is a CenExel Center of Excellence?

CenExel Centers of Excellence provide unparalleled medical and scientific support in the design and execution of clinical trials. Their attention to detail assures quality, reliable results and has helped CenExel to consistently achieve and exceed patient recruitment goals. They have conducted thousands of studies, the variety and complexity of which have resulted in a great depth of experience and insight for the principal investigators and research staff in each facility. CenExel Centers of Excellence deliver the engagement, expertise, and results to ensure that clients achieve their clinical research goals.

How do clinical trials work?

The study procedures and process will vary depending on the type of clinical trial you participate in. Before you begin a study, the process and all procedures for that study will be explained to you. Throughout the study, the Study Coordinator and the Principal Investigator will assist you and can answer any questions you have. They will check your health at the beginning of the trial, give you specific instructions for participating in the trial, monitor you carefully during the trial, and stay in touch with you after the study.

Some clinical trials involve more tests and doctor visits than you would normally have for your illness or condition. Your participation will be most successful if you carefully follow all instructions you are given and stay in contact with the research staff.

How safe are clinical studies?

There are many safeguards in place that all companies must follow when conducting clinical trials.

The Food and Drug Administration (FDA) is the regulatory agency that oversees all clinical research conducted in the United States. It is their responsible to protect the rights and as much as possible, the welfare of subjects participating in clinical trials. They ensure that data collected from clinical trials is of the highest quality and they are the agency that determines whether a new treatment should be sold in the US. Several organizations and individuals are governed by FDA regulations including clinical investigators, sponsors (the companies developing the treatments), Contract Research Organizations (companies that help conduct the studies), and Institutional Review Boards (groups that are responsible for ensuring the safety and welfare of study participants).

Good Clinical Practice (GCP) guidelines are another safeguard implemented to protect the safety of subjects. These guidelines encompass federal regulations and industry-accepted standards that govern clinical trials on humans. These regulations and standards apply to the conduct of the studies, record keeping, informed consent of subjects, collection of scientific data, and submission of information needed for the FDA to determine whether a new treatment should or should not be sold in the US. All companies must follow these guidelines when conducting clinical research.

An Institutional Review Board (IRB) is a committee that is formally tasked by an institution to review, approve, and monitor research involving human subjects. IRBs ensure that the risks to subjects are minimized; that subjects are adequately informed about the trial and the implications it will have on their treatment; that study protocols are modified, when necessary, to ensure safety; that risks are reasonable in relation to the anticipated benefits and the importance of the knowledge to be gained; that subject selection is equitable and that no classes of patients are discriminated against; that informed consent is obtained; that there is a provision for safety monitoring in the research plan; and that here are adequate provisions for the privacy and confidentiality for subjects and the data collected.

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