CenExel Center of Excellence News

DTx in Schizophrenia

Clinical Trials of Prescription Digital Therapeutics for Schizophrenia June 26, 2024 By Haig Goenjian, MD Prescription digital therapeutics (DTx) are paving the way for groundbreaking advancements in treating challenging conditions like #schizophrenia and #depression....

Psychedelics in Developmental Stuttering

Psychedelics in developmental stuttering to modulate brain functioning: a new therapeutic perspective? PERSPECTIVE article Front. Hum. Neurosci., 18 June 2024 Sec. Speech and Language Volume 18 - 2024 | https://doi.org/10.3389/fnhum.2024.1402549 Giuseppe Pasculli,...

Antipsychotic Demonstrates Efficacy

Investigational Antipsychotic Demonstrates Efficacy Without Blocking Dopamine Receptor June 7, 2024 By Kenneth J. Bender, PharmD, MA Investigational agent KarXT is a first-in-class muscarinic receptor agonist demonstrating antipsychotic efficacy and safety in short-...

Moving Forward with Muscarinics

Moving Forward with Muscarinics June, 2024 By Haig Goenjian, MD, Principal Investigator, CenExel CNS Read the article on Southern California PSYCHIATRIST here: https://www.socalpsych.org/2024/06/june-2024/  

Psychometric Rater Stress and Burnout

Salt Lake City, Utah, May 29, 2024 (GLOBE NEWSWIRE) -- Poster presented today at American Society of Clinical Pharmacology (ASCP) Annual Meeting in Miami Beach, Florida, shows:   High levels of work stress and burnout in raters for psychiatric and neurological...

Effects of the selective AMPA modulator

Effects of the selective AMPA modulator NBI-1065845 on the pharmacokinetics of midazolam or ethinyl estradiol–levonorgestrel in healthy adults Swan Lin, Adrian Ionescu, Jessica Maynard-Scott, Mike Kennedy, David P. Walling, Maura Furey, Jaskaran B. Singh First...

Xanomeline-Trospium Chloride in Schizophrenia

Efficacy and Safety of Xanomeline-Trospium Chloride in Schizophrenia A Randomized Clinical Trial Inder Kaul, MD, MPH1; Sharon Sawchak, RN1; David P. Walling, PhD2; et alCarol A. Tamminga, MD3; Alan Breier, MD4; Haiyuan Zhu, PhD1; Andrew C. Miller, PhD1; Steven...

Make or Break An Analgesic Non-Opioid Trial

Unknowns That Can Make or Break a Non-Opioid Analgesic Clinical Trial New and renewed approaches to improve chances of success in developing non-addictive drugs for chronic pain. March 21, 2024 By Todd M. Bertoch, MD Many pitfalls are associated with clinical trials...