Sciatica Leg Pain Study

We are conducting a study to test an injection for pain in individuals that have neuropathic pain from Lumbosacral Radiculopathy (Sciatica leg pain)

Sciatica Leg Pain Study

We are conducting a study to test an injection for pain in individuals that have neuropathic pain from Lumbosacral Radiculopathy (Sciatica leg pain)

What to expect:

We are conducting a study testing an investigational injection to help reduce the pain associated with Lumbosacral Radiculopathy or “Sciatica”(pain that radiates down the legs from the lower back). Male and female participants, ages 18-70, who are selected to participate in the study may receive no cost investigational injection, study related care and be compensated for time and travel.

The study will consist of a screening visit, a dosing visit within 28 days of screening, up to 6 follow-up calls, and up to 7 follow-ups during study participation, which lasts up to 13 months.

What is Lumbosacral Radiculopathy?

Lumbosacral radiculopathy is a condition in which a disease process affects the function of one or more lumbosacral nerve roots. The most common cause is disc herniation or degenerative spinal stenosis leading to root compression. This can manifest as pain, numbness, or weakness of the buttock and leg. This causes pain in the leg rather than in the lumbar spine.

What causes Lumbosacral Radiculopathy?

There are many potential causes of radiculopathy, including poor lifting technique, poor posture, and back injuries. Radiculopathy can be caused by a variety of conditions or injuries, including: a herniated disc, when a disc protrudes, compressing the nerve root.

What is the difference between sciatica and lumbosacral radiculopathy?

Radiculopathy refers to nerve irritation caused by damage to the disc between the vertebrae. When nerves are irritated in the low back from degenerative disc disease, the condition is called lumbar radiculopathy, and it often causes the commonly recognized “sciatica” pain that shoots down a lower extremity.


To be considered for the study, please fill out the form or call 801-261-2000.


Studies are currently available for qualified participants.


No health insurance required


Compensation for time up to $1,200


Pain radiating down one leg
Must have had the pain for at least 8 weeks but no longer than 9 months


Male / Female


18-70 years old


650 East 4500 South Suite #100
Salt Lake City, UT 84107

We are committed to keeping your personal information safe and secure. Any information collected will not be sold or shared with third parties.

State-of-the-art Facilities

CenExel JBR is Utah’s premier clinical research organization. For over two decades, we’ve helped improve the quality of life for everyone by researching new medications and treatments. Our state-of-the-art facility is held to the highest standards of cleanliness and quality.

Board-certified Physicians

Your safety is our greatest concern. Every procedure at CenExel JBR is overseen by expert medical staff and performed by some of the most well-respected board-certified physicians in the industry, each with many years of experience in their respective specialties.

Standard Procedures

Rest assured, you are not signing up for an “experimental” method. Our research is focused on the investigational medications given after that procedure.

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