Osteoarthritis of the Knee

Do you suffer from knee osteoarthritis? JBR Clinical Research will soon be conducting a clinical research study of an investigational medication to help with moderate to severe OA of the knee

Osteoarthritis of the Knee

Do you suffer from knee osteoarthritis? JBR Clinical Research will soon be conducting a clinical research study of an investigational medication to help with moderate to severe OA of the knee

Why participate in this clinical research study?

Clinical studies are the fastest and safest way to find the effectiveness of pain medications that work and are only possible with the help of participants like you. Compensation varies by study, time involved, and whether you complete all visits and procedures in the study. Every volunteer study at JBR Clinical Research is approved and monitored by an Institutional Review Board (IRB) to make sure the risks are as low as possible and are worth any potential benefits to the volunteer.

What to expect:

Those that qualify for this study will be asked to complete a screening visit and treatment visit


What is Osteoarthritis of the Knee?

Osteoarthritis is the most common form of arthritis in the knee. It is a degenerative, “wear-and-tear” type of arthritis that occurs most often in people 50 years of age and older, but may occur in younger people, too. It is a type of arthritis that occurs when the protective flexible tissue (cartilage) at the ends of bones wears down and gradually wears away

What are the symptoms of Osteoarthritis of the Knee?

pain that increases when you are active, but gets a little better with rest
• swelling
• feeling of warmth in the joint
• stiffness in the knee, especially in the morning or when you have been sitting for a while
• decrease in mobility of the knee, making it difficult to get in and out of chairs or cars, use the stairs, or walk
• creaking, crackly sound that is heard when the knee moves

What causes Knee Osteoarthritis?

• Age. The ability of cartilage to heal decreases as a person gets older.

• Weight. Weight increases pressure on all the joints, especially the knees. Every pound of weight you gain adds 3 to 4 pounds of extra weight on your knees.

• Heredity. This includes genetic mutations that might make a person more likely to develop osteoarthritis of the knee. It may also be due to inherited abnormalities in the shape of the bones that surround the knee joint.

• Gender. Women ages 55 and older are more likely than men to develop osteoarthritis of the knee.
• Repetitive stress injuries. These are usually a result of the type of job a person has.

People with certain occupations that include a lot of activity that can stress the joint, such as kneeling, squatting, or lifting heavy weights (55 pounds or more), are more likely to develop osteoarthritis of the knee because of the constant pressure on the joint.

• Athletics. Athletes involved in soccer, tennis, or long-distance running may be at higher risk for developing osteoarthritis of the knee. That means athletes should take precautions to avoid injury. However, it’s important to note that regular moderate exercise strengthens joints and can decrease the risk of osteoarthritis. In fact, weak muscles around the knee can lead to osteoarthritis.

• Other illnesses. People with rheumatoid arthritis, the second most common type of arthritis, are also more likely to develop osteoarthritis. People with certain metabolic disorders, such as iron overload or excess growth hormone, also run a higher risk of osteoarthritis.

To be considered for the study, please fill out the form or call 801-261-2000.


Studies are currently available for qualified participants.


No health insurance required


Compensation for time TBD


BMI must be less than 40kg/m2
Confirmation of moderate to severe OA pain


Male / Female


18+ years old


650 East 4500 South Suite #100
Salt Lake City, UT 84107

We are committed to keeping your personal information safe and secure. Any information collected will not be sold or shared with third parties.

State-of-the-art Facilities

CenExel JBR is Utah’s premier clinical research organization. For over two decades, we’ve helped improve the quality of life for everyone by researching new medications and treatments. Our state-of-the-art facility is held to the highest standards of cleanliness and quality.

Board-certified Physicians

Your safety is our greatest concern. Every procedure at CenExel JBR is overseen by expert medical staff and performed by some of the most well-respected board-certified physicians in the industry, each with many years of experience in their respective specialties.

Standard Procedures

Rest assured, you are not signing up for an “experimental” methods. JBR Clinical Research only performs standard surgery procedures  as if you were at any other hospital or clinic. Our research is focused on the investigational medications given after that procedure.

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