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Major Depression Studies

Available for qualified participants

Major Depression Studies

Available for qualified participants

What is Major Depression?

Major depression is a diagnosis coming from the presence of multiple symptoms of depression, possibly including depressed mood, changes in appetite, changes in sleep, and loss of interest in activities previously enjoyed.

Major depression may also impact concentration and motivation, making it difficult to get out of bed in the morning. Suicidal thinking is sometimes present. Patients experiencing major depression may feel worthless, guilty, helpless, and hopeless.

When enough of these symptoms have been present for at least two weeks, the diagnosis of major depression is appropriate.

What are Depression Studies? 

Medical research helps doctors and researchers learn more about disease and improve healthcare, advancing innovative medicines, devices, and therapies. These studies involve people like you and are at the heart of all medical advances to prevent, detect, or treat disease. Clinical studies for depression determine if the new treatment, prevention, and behavior approaches are safe and effective.

At CenExel CBH, we offer both inpatient and outpatient depression studies. We also have trials focusing on treatment-resistant depression, which has not responded to medication or psychotherapy.

Who Should Participate?

While every study has different, specific criteria, generally in order to qualify, you must:

  • Be between the ages of 18-65 years
  • Have a diagnosis of Major Depressive Disorder
  • Be experiencing a current depressive episode of at least 8 weeks
  • Be in good physical health

Participating in a depression clinical trial is a good option to consider if you are experiencing depression and your current medications are not working well or enough. If you are in good physical health, and want to explore some new treatments for your depression, contact us today.

What are the Risks and Benefits?

After researchers extensively test new treatments or procedures in a lab, the most promising and safe treatments are approved for clinical trials. As these new treatments move through a series of clinical research steps called phases, we gain more information about the treatments’ risks and effectiveness. Safety is always the top priority, and clinical testing ceases if patient safety is compromised.

In addition to directly advancing the development of the newest medicines and therapies, participants may receive these new treatments themselves. They will receive extra care and attention from clinical trial staff. Study participants will also receive compensation for time and travel. Clinical trials offer hope for many people and an opportunity to help researchers and physicians find better treatments.

What to Expect from CenExel CBH?

Each depression trial at CenExel CBH is run by a Study Coordinator and a Principal Investigator – an expert physician with extensive background in both mental health and clinical research. Before beginning participation, the study process and all procedures are explained thoroughly. During the entire study, the Study Coordinator and Principal Investigator assist participants, performing health checks, offering guidance and instruction, carefully monitoring, answering any questions, and even staying in touch after the study.

The state-of-the-art CenExel CBH facility was designed with the best equipment and surroundings to ensure patient safety and comfort.

We have helped tens of thousands of patients in similar studies.
Space in this study is limited. To be considered, please fill out the form or call 301-251-4702.



No health insurance requirement


Compensation for time and travel up to $2,400


Diagnosed with Major Depressive Disorder and experiencing a depressive episode of at least 8 weeks


Male / Female


18-65 years old


State of the Art Facilities

CBH is Maryland’s premier clinical research organization. For a decade, we’ve helped improve the quality of life for everyone by researching new medications and treatments. Our state-of-the-art facilities are held to the highest standards of cleanliness and quality.

Board Certified Physicians

Your safety is our greatest concern. Every procedure at CBH is overseen by expert medical staff and performed by some of the most well-respected board-certified physicians in the industry, each with many years of experience in their respective specialties.

FDA Approved Procedures

Rest assured, you are not signing up for treatment with “experimental” methods. CBH only uses FDA approved methods as if you were at any other hospital or clinic. Our research is focused on the medication associated with those methods.

Frequently asked questions

What is a CenExel Center of Excellence?

CenExel Centers of Excellence provide unparalleled medical and scientific support in the design and execution of clinical trials. Their attention to detail assures quality, reliable results and has helped CenExel to consistently achieve and exceed patient recruitment goals. They have conducted thousands of studies, the variety and complexity of which have resulted in a great depth of experience and insight for the principal investigators and research staff in each facility. CenExel Centers of Excellence deliver the engagement, expertise, and results to ensure that clients achieve their clinical research goals.

How do clinical trials work?

The study procedures and process will vary depending on the type of clinical trial you participate in. Before you begin a study, the process and all procedures for that study will be explained to you. Throughout the study, the Study Coordinator and the Principal Investigator will assist you and can answer any questions you have. They will check your health at the beginning of the trial, give you specific instructions for participating in the trial, monitor you carefully during the trial, and stay in touch with you after the study.

Some clinical trials involve more tests and doctor visits than you would normally have for your illness or condition. Your participation will be most successful if you carefully follow all instructions you are given and stay in contact with the research staff.

How safe are clinical studies?

There are many safeguards in place that all companies must follow when conducting clinical trials.

The Food and Drug Administration (FDA) is the regulatory agency that oversees all clinical research conducted in the United States. It is their responsible to protect the rights and as much as possible, the welfare of subjects participating in clinical trials. They ensure that data collected from clinical trials is of the highest quality and they are the agency that determines whether a new treatment should be sold in the US. Several organizations and individuals are governed by FDA regulations including clinical investigators, sponsors (the companies developing the treatments), Contract Research Organizations (companies that help conduct the studies), and Institutional Review Boards (groups that are responsible for ensuring the safety and welfare of study participants).

Good Clinical Practice (GCP) guidelines are another safeguard implemented to protect the safety of subjects. These guidelines encompass federal regulations and industry-accepted standards that govern clinical trials on humans. These regulations and standards apply to the conduct of the studies, record keeping, informed consent of subjects, collection of scientific data, and submission of information needed for the FDA to determine whether a new treatment should or should not be sold in the US. All companies must follow these guidelines when conducting clinical research.

An Institutional Review Board (IRB) is a committee that is formally tasked by an institution to review, approve, and monitor research involving human subjects. IRBs ensure that the risks to subjects are minimized; that subjects are adequately informed about the trial and the implications it will have on their treatment; that study protocols are modified, when necessary, to ensure safety; that risks are reasonable in relation to the anticipated benefits and the importance of the knowledge to be gained; that subject selection is equitable and that no classes of patients are discriminated against; that informed consent is obtained; that there is a provision for safety monitoring in the research plan; and that here are adequate provisions for the privacy and confidentiality for subjects and the data collected.