Primer on the Autonomic Nervous System – 4th Edition

Dec 28, 2022 | Blog, CenExel CNS, Psychiatry

We congratulate Brett A. English, PharmD, PhD VP, Clinical Sciences and Development CenExel, on his textbook chapter on cholinergic neurotransmission in the autonomic nervous system, published in The Primer on the Autonomic Nervous System – 4th Edition.

This book provides a concise and accessible overview of autonomic neuroscience for students, scientists, and clinicians. The book’s 142 chapters draw on the expertise of more than 215 basic scientists and clinicians who discuss key information on how the autonomic nervous system controls the body, particularly in response to stress. This new edition also focuses on the translational crossover between basic and clinical research. In addition to comprehensively covering all aspects of autonomic physiology and pathology, topics such as psychopharmacology decoding and modulating nerve function are also explored.  (

An accomplished clinical researcher, basic scientist, and psychiatric pharmacist, Dr. English joined Apex in 2021 to provide strategic direction and leadership to the Scientific Affairs team, medical/scientific guidance and training to clinical project teams, and consultation and support services to pharmaceutical companies. Specialized in translational neurosciences, he has deep expertise in early phase program planning and electrophysiology, imaging, and pharmacodynamic biomarker applications.

Dr. English brought with him to Apex over 15 years of experience as a clinical scientist and Principal Investigator on investigator-initiated and industry-sponsored Phase I-III trials in CNS disorders. He also has experience serving as a Product Team Lead and Clinical Development Lead for numerous compounds in early phase development in the CNS therapeutic area. In addition to his clinical research experience, He has also utilized novel high-throughput pharmacogenetic screening methods to discover novel variants in neuro-transporter proteins and their association with psychiatric disorders.

Dr. English is now part of the Clinical Sciences by CenExel leadership team, where his experience in basic biomedical research, including preclinical models of neuropsychiatric disorders utilizing several in-vitro and in-vivo behavioral and physiological experimental paradigms, has earned him praise and respect among his peers and colleagues.

Learn more about Clinical Sciences by CenExel.