News at CenExel

Placebo-Control Reminder Script

General medicine studies are not immune to the placebo effect, where 30-40% of patients report improved subjective and objective outcomes in general medical studies (Hrobjartsson & Gotzsche, 2001). The high placebo response has been shown to be increasing as time progresses (Kemp et al., 2010; Loebel et al., 2010; Rief et al., 2009; Tuttle et al., 2015), with such ramifications as several pharma companies reducing or closing their psychiatric as well as general medicine R&D, increased costs for drug development, more inconclusive and failed trials, and delays in the development of new medications (Alphs et al., 2012).

A First-Time Investigation of a Subject Intervention to Reduce the Placebo and Nocebo Effects:​ A Multicenter, Randomized, Single-Blind, All Placebo Study of a​ Placebo-Control Reminder Script for Subjects with Major Depression​

CenExel is proud to highlight the poster presented at the Annual CNS Summit Meeting,​ November 2018, Boca Raton, FL.​ ​ABSTRACT Introduction: This investigation is the first known that empirically explores if educating subjects about key causes of the placebo effect...