News at CenExel

Placebo-Control Reminder Script

General medicine studies are not immune to the placebo effect, where 30-40% of patients report improved subjective and objective outcomes in general medical studies (Hrobjartsson & Gotzsche, 2001). The high placebo response has been shown to be increasing as time progresses (Kemp et al., 2010; Loebel et al., 2010; Rief et al., 2009; Tuttle et al., 2015), with such ramifications as several pharma companies reducing or closing their psychiatric as well as general medicine R&D, increased costs for drug development, more inconclusive and failed trials, and delays in the development of new medications (Alphs et al., 2012).

PCRS in Depression Clinical Trials

CenExel is proud to highlight the poster presented at the Annual International Society for CNS Clinical Trials and Methodology (ISCTM) Meeting, February 2019, Washington, DC. ABSTRACT Introduction: Although the placebo effect continues to persist within depressive...

PCRS on Subjects with Major Depression​

CenExel is proud to highlight the poster presented at the Annual CNS Summit Meeting,​ November 2018, Boca Raton, FL.​ ​ABSTRACT Introduction: This investigation is the first known that empirically explores if educating subjects about key causes of the placebo effect...

Subjects With Major Depression and PCRS

CenExel is proud to highlight the poster presented at the​ Annual Meeting of the International Society for CNS Clinical Trials and Methodology Conference, February 2018, Washington, DC. ABSTRACT​ Introduction: The challenge to reliably achieve signal detection in...