Amyloid PET Imaging

Brain amyloid imaging technology can aid in the diagnosis of people with cognitive impairment when considered along with other clinical information, and when performed according to standardized protocols by trained staff.

What is Amyloid PET Imaging?

A brain positron emission tomography (PET) scan is a procedure that takes 3D pictures of the brain and shows if (β)-amyloid deposits (plaques) are on the brain.
A tracer is used to bind to amyloid and make it appear on the scan. Therefore, it shows if there is (β)-amyloid deposits (plaques) in your brain.
This test has been studied by the American College of Radiology in regards to its assistance in diagnosing Alzheimer’s Disease.

What is amyloid?

Beta (β)-amyloid deposits, also called plaques, are found on the brains of people with Alzheimer’s disease. Scientists and researchers think plaques contribute to memory loss and other symptoms of Alzheimer’s disease.

How is an amyloid PET scan performed?

A small amount of the tracer is injected into your vein (IV). The tracer travels through your bloodstream and collects in your brain. The tracer sticks to (β)-amyloid deposits (plaques) if there is any in your brain.
A waiting period of twenty (20) to ninety (90) minutes may take place to allow the tracer to travel through your body.
You will lie down on a narrow table and the technician will secure your head to the holder with a strap. The table will slide into the scanner, which is a large machine with a round, doughnut-shaped hole in the middle. Only your head will be in the scanner. You must lie still during the scan so that clear pictures of your brain can be created.
The PET scan only takes up to twenty (20) minutes.

Why is amyloid PET imaging important in clinical research?

One or more PET scans are required for most Alzheimer’s clinical trials.
The scans show whether you have (β)-amyloid deposits (plaques) in your brain. This can determine if you can participate in a study or not. It also is a measurement that will be used to test if the treatment you are receiving effects the (β)-amyloid deposits (plaques) in your brain.

What are the risks of amyloid PET imaging?

You may feel a sting when the tracer is injected into your vein (IV).
You may experience mild side effects of the tracer such as redness and irritation at the injection site, nausea, dizziness or more.
There is a slight chance of having an allergic reaction to the tracer.
There is a small amount of radiation used in an amyloid PET scan. More than half the radiation will leave your body within two (2) hours of being injected.
You may experience anxiety if you are afraid of small spaces (claustrophobic), but you may be given a medicine to help you feel sleepy or less anxious.
The PET scan itself causes no pain. You may experience some discomfort because the table may be hard or cold, but you may request a pillow and a blanket.

Learn more: 732-341-9500

Update on COVID-19

To: Our Sponsors, CROs, Patients, and Employees

At CenExel Clinical Research, our top priorities are the safety and health of our patients and employees. For our Centers of Excellence to provide the highest quality of clinical research, we established and maintain a COVID-19 Task Force with representatives from every Center. The Task Force is charged with continuous monitoring of the pandemic and providing guidance and communication.

Our clinical operations continue, and we have implemented the following additional safety measures:

Enhanced screening of everyone entering any of our facilities before they are admitted into our offices or clinical areas
Reinforced internal communication regarding the COVID-19 situation, CDC and SHRM recommendations, digital team meetings, and the importance of using sick leave for anyone who has signs, symptoms, or recent exposure to someone with suspected or diagnosed COVID-19
Additional cleaning and disinfecting materials provided through our clinic and office areas
Cross-training and preparations for contingency plans if key staff need to stay home

We will continue to monitor the current situation, coordinate with the proper authorities, and update our policies and procedures as needed to ensure the safety of our patients and employees.