At CenExel we care when it comes to the science of life.

Who We Are

We are a leading clinical research site and patient network serving the life sciences in the pursuit of life-changing therapies.
Who we are triangular graphic with 40 year anniversary badge
Our inspiration is to transform the quality of life through exceptional medical research with an unwavering commitment to quality, the patient experience, and our customers.

Who We Serve

We are dedicated to helping organizations and patients find new cures and treatments to improve the quality of life globally. Our approach ensures unparalleled patient engagement, medical staff expertise and actionable results.
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Pharma & Biotech

The world’s most innovative companies trust CenExel to be the best resource to help develop life-changing therapies and inovative biotechnology for a healthier society.
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CROs

Clinical Research Organizations need established sites and patient recruitment channels to manage cost relative to time and guarantee accurate data.
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Patients

At our core, we are all about the patient experience. Participants in our research studies receive first-class treatment from board-certified physicians – often receiving care they wouldn’t otherwise have access to.

Our History

Continuing a proud legacy of clinical research excellence

Founded in 2018 as JBR Clinical Research, we began our journey. In 2019, JBR Clinical Research partnered with Webster Equity Partners to fuel our growth in the marketplace. In 2019 we rebranded as CenExel, marking the initiation of our legacy.

Established on our Centers of Excellence model, the name “CenExel” honors our commitment to Centers (Cen) and Excellence (Exel) across our vast clinical research site network. Each Center of Excellence excels in the delivery of outstanding medical research with a commitment to patients, sponsors, and the communities we serve.

Specializing in CNS and Early Phase clinical research, we have a 40+ year rich history, with our first site dating back to 1982. While we continue to grow organically, our expansion has been bolstered by number of strategic acquisitions that both broadens our portfolio and adds scale to our offering.

Today, CenExel is a leading site network supporting today’s most progressive life science companies. With over 1200 employees across 18 U.S. metro areas, we help pharma, biotech and CROs bring innovative treatments to patients that need them the most.

Executive Team

Led by the best and the brightest

CenExel has assembled a highly cohesive executive leadership team with in-depth industry experience and extensive knowledge across all aspects of clinical research. With an unwavering commitment to innovation in clinical trials, they collectively serve as our driving force, leading our entire organization in supporting life sciences organizations in the pursuit of life-changing medicines for patients.

Meet the leaders dedicated to improving the landscape of global human health.

Corporate Leadership

Ryan Brooks

Ryan Brooks

Chief Executive Officer and Executive Chairman of the Board

Steve Killian

Steve Killian

Chief Financial Officer

Ryan Brooks
Executive Chairman and interim Chief Executive Officer

Ryan Brooks serves as the Executive Chairman of the Board and Interim CEO for CenExel, bringing extensive expertise and a track record of transformative achievements in the healthcare industry.

As Executive Chairman of the Board, Ryan architect’s CenExel’s broader strategies and oversees its long-term trajectory, collaborating closely with the board.

In his role as Interim CEO, he guides CenExel’s strategic direction, manages operations, and ensures the company meets its objectives with precision and effectiveness. Ryan’s leadership fosters innovation and a commitment to advancing life-changing therapies through exceptional medical research, driving the company’s growth and performance.

In addition to his roles at CenExel, Ryan’s career includes significant positions at Abbott, Boston Scientific, and St. Jude Medical, along with considerable experience in healthcare venture capital and public equities. In 2018, he played a key role with Webster Equity Partners in founding CenExel, following the sale of his interest in a clinical research site that became the first in CenExel’s expansive network.

Ryan’s dynamic leadership and visionary approach will continue to propel CenExel’s success and impact on clinical development. He holds a Bachelor’s Degree from Brigham Young University and an MBA from Gonzaga University Graduate School of Business.

Steve Killian
Chief Financial Officer

Steve Killian leads and contributes to highly effective healthcare organizations. He is dedicated to being a forward-thinking senior executive and committed to work efforts that allow cultivation of expertise in all aspects of operational and financial management. Steve possesses excellent financial, communication, and problem-solving skills with a team-driven focus. He’s a big picture and results-oriented, visible leader with success in building up executive teams for execution of growth strategies.

Patrick McLaughlin

Patrick McLaughlin

Chief Operating Officer

Larry Ereshefsky, PharmD, BCPP

Larry Ereshefsky, PharmD, BCPP

Chief Scientific Officer, Early Phase

Diana Shuster, PhD

Diana Shuster, PhD

Vice President of Clinical Sciences

Patrick McLaughlin
Chief Operating Officer

Patrick McLaughlin, Chief Operating Officer, is a highly experienced leader in the life sciences sector, with nearly 30 years of expertise.

In his current role, Patrick is responsible for driving the development of organizational and cross-entity strategic plans that promote growth, integration, and collaboration with both internal and external stakeholders. He directs organizational development activities with a focus on standardization, efficiency, cost-effectiveness, continuous performance improvement, and regulatory compliance, while also adapting to innovations in clinical research.

Patrick’s career in clinical research began in 1996 when he was appointed President of the Institute of Clinical Research (ICR), a full-service, multi-specialty dedicated research site. During his tenure, Patrick played a pivotal role in negotiating the sale of ICR to Protocare, a Site Management Organization, which recognized ICR as one of its premier sites, setting a standard for other Protocare sites.

In the same year, Patrick was recruited as the Executive Director of Advanced Clinical Research Institute in Anaheim, CA, where he successfully led the organization into the Phase I clinical research sector, expanding its focus beyond Phase II-IV studies. In 2007, Patrick was instrumental in the purchase of an 8,800-square-foot, dedicated Phase I facility and rebranded the company as Anaheim Clinical Trials (ACT). ACT grew into a leading and innovative player in the industry, ultimately being acquired by CenExel in 2019.

Patrick earned a degree in Business Administration from the University of Texas at Austin.

Larry Ereshefsky, PharmD, BCPP
Chief Scientific Officer, Early Phase

Dr. Ereshefsky is an internationally recognized key opinion leader in clinical translational central nervous system research with a proven track record in designing and performing first-in-human, proof-of-concept, and a broad range of Phase I clinical pharmacology studies. With over 30 years’ experience leading early phase research sites, he is utilized as a global resource within CenExel, providing support to ensure consistency and quality across sites. Dr. Ereshefsky is actively involved in strategic planning for compound development. He helps design translational research programs and define the critical path towards regulatory approval. He has extensive experience working with regulatory agencies and developing strategic plans to address compound differentiation and reimbursement challenges.

Diana Shuster, PhD
Vice President of Clinical Sciences

Dr. Diana Shuster, PhD, serves as Vice President of Clinical Sciences at CenExel, bringing over a decade of expertise in Translational and Early Phase central nervous system research. Her role encompasses the design and execution of first-in-human, proof-of-concept, and diverse Phase I clinical pharmacology studies. With a background spanning big pharma, CROs, and TechBio, Dr. Shuster has significantly contributed to advancing rare disease compounds.

In her capacity as Vice President, Dr. Shuster is dedicated to integrating her multifaceted expertise to ensure consistency and quality across global research sites. Actively engaged in strategic planning, she specializes in designing translational research programs and navigating the critical path to regulatory approval. Driven by a commitment to de-risking early phase drug development, she employs innovative strategies, including continuous CSF sampling, QEEG, ERPs, PSG, fMRI, PET, and cognitive paradigms.

Andrew Birschbach

Andrew Birschbach

VP, Corporate Development & Strategic Finance

Mark Trimble, SPHR

Mark Trimble, SPHR

VP, Human Resources & Administration

Hollie DeSmet

Hollie DeSmet

VP, Regulatory and Quality Assurance

David Chia

David Chia

Chief Information Officer

Andrew Birschbach
VP, Corporate Development & Strategic Finance

Andrew is a strategic finance professional with experience spanning Fortune 10 public companies to growth-stage, private-equity-backed businesses. His experience includes mergers and acquisitions, business development, operational financial modeling, budgeting, and analysis. Most recently, he was a manager of finance at Alignment Healthcare, an innovative, information-enabled Medicare Advantage company where he provided detailed operational modeling, forecast scenario analysis, analysis for new market expansion, and M&A opportunity evaluation. Prior to Alignment, he was a mergers and acquisitions Senior Associate at UnitedHealth Group’s Corporate Development & Strategy Team.

Mark Trimble, SPHR
VP, Human Resources & Administration

Mark is a Human Resources Executive with 20+ years of experience in HR operations and management. Throughout his career he has provided leadership and guidance in the conceptualization, implementation, and management of HR strategies, organizations, programs, and policies. Mark has held several corporate HR leadership positions within the HR outsourcing, life sciences, and healthcare industries.

In his most recent role, prior to joining CenExel, Mark held the position of Regional Vice President of HR Operations for Oasis Outsourcing, a global leader in the Professional Employer Organization industry. In this position, Mark drove positive change through day-to-day operational and financial leadership and competitively evolved HR service offerings for clients in the healthcare and manufacturing industries.

As an HR executive with a strong business acumen, Mark has successfully implemented people-based solutions and the HR function to ensure achievement of corporate business goals. As both an HR strategist and hands-on practitioner, Mark’s areas of expertise include culture alignment and change management, employment law and regulatory compliance, compensation planning, team building, business process and policy formation, talent engagement, and HR consulting.

Mark holds a Bachelor of Science degree in Psychology from BYU and is also certified as a Senior Professional in Human Resources (SPHR).

Hollie DeSmet
VP, Regulatory and Quality Assurance

Hollie DeSmet serves as the Vice President of Regulatory and Quality Assurance at CenExel. In her role she leverages her knowledge of CFR, ICH GCP, and FDA Guidance to ensure good clinical practice, focusing on safe, ethical, and high-quality research across CenExel sites.

Hollie joined the Cenexel team from the first site acquired where she held the position of Director of Quality and Compliance. She has a deep familiarity with all CenExel sites and enjoys collaborating with key personnel to oversee the development and implementation of CenExel Standard Operating Procedures, including consistent training practices, quality assurance procedures, and best regulatory practices. She firmly believes that communication is the key to consistency and consistency is the key to quality. Hollie has a passion for swift regulatory processing to ensure a fast-paced study start-up and producing the highest quality data possible for successful study execution.

David Chia
Chief Information Officer

David Chia oversees IT strategy, implementation, and operations at CenExel – as well as driving the adoption of new technologies, information security, data analytics, and system industry compliance.

David is a 26-year technology leader experienced in IT consulting, development, analytics, and operations. Over the last 13 years he has worked in progressive leadership roles at HCA Healthcare, overseeing IT hospital operations and division application development for 19 hospitals and physician practices over 5 western states. He has received several accolades for his efforts including Innovator of the Year for development of several IT applications and data tools.

David is a graduate of Brigham Young University with degrees in MIS and an MBA. His passion, execution and servant leadership drive him to partner across CenExel to improve the delivery of studies and care through innovation and technology.

Ryan Brooks

Ryan Brooks

Chief Executive Officer and Executive Chairman of the Board

Ryan Brooks

Ryan Brooks serves as the Executive Chairman of the Board and Interim CEO for CenExel, bringing extensive expertise and a track record of transformative achievements in the healthcare industry.

As Executive Chairman of the Board, Ryan architect’s CenExel’s broader strategies and oversees its long-term trajectory, collaborating closely with the board.

In his role as Interim CEO, he guides CenExel’s strategic direction, manages operations, and ensures the company meets its objectives with precision and effectiveness. Ryan’s leadership fosters innovation and a commitment to advancing life-changing therapies through exceptional medical research, driving the company’s growth and performance.

In addition to his roles at CenExel, Ryan’s career includes significant positions at Abbott, Boston Scientific, and St. Jude Medical, along with considerable experience in healthcare venture capital and public equities. In 2018, he played a key role with Webster Equity Partners in founding CenExel, following the sale of his interest in a clinical research site that became the first in CenExel’s expansive network.

Ryan’s dynamic leadership and visionary approach will continue to propel CenExel’s success and impact on clinical development. He holds a Bachelor’s Degree from Brigham Young University and an MBA from Gonzaga University Graduate School of Business.

Steve Killian

Steve Killian

Chief Financial Officer

Steve Killian

Steve Killian leads and contributes to highly effective healthcare organizations. He is dedicated to being a forward-thinking senior executive and committed to work efforts that allow cultivation of expertise in all aspects of operational and financial management. Steve possesses excellent financial, communication, and problem-solving skills with a team-driven focus. He’s a big picture and results-oriented, visible leader with success in building up executive teams for execution of growth strategies.

Patrick McLaughlin

Patrick McLaughlin

Chief Operating Officer

Patrick McLaughlin

Patrick McLaughlin, Chief Operating Officer, is a highly experienced leader in the life sciences sector, with nearly 30 years of expertise.

In his current role, Patrick is responsible for driving the development of organizational and cross-entity strategic plans that promote growth, integration, and collaboration with both internal and external stakeholders. He directs organizational development activities with a focus on standardization, efficiency, cost-effectiveness, continuous performance improvement, and regulatory compliance, while also adapting to innovations in clinical research.

Patrick’s career in clinical research began in 1996 when he was appointed President of the Institute of Clinical Research (ICR), a full-service, multi-specialty dedicated research site. During his tenure, Patrick played a pivotal role in negotiating the sale of ICR to Protocare, a Site Management Organization, which recognized ICR as one of its premier sites, setting a standard for other Protocare sites.

In the same year, Patrick was recruited as the Executive Director of Advanced Clinical Research Institute in Anaheim, CA, where he successfully led the organization into the Phase I clinical research sector, expanding its focus beyond Phase II-IV studies. In 2007, Patrick was instrumental in the purchase of an 8,800-square-foot, dedicated Phase I facility and rebranded the company as Anaheim Clinical Trials (ACT). ACT grew into a leading and innovative player in the industry, ultimately being acquired by CenExel in 2019.

Patrick earned a degree in Business Administration from the University of Texas at Austin.

Larry Ereshefsky, PharmD, BCPP

Larry Ereshefsky, PharmD, BCPP

Chief Scientific Officer, Early Phase

Larry Ereshefsky, PharmD, BCPP

Dr. Ereshefsky is an internationally recognized key opinion leader in clinical translational central nervous system research with a proven track record in designing and performing first-in-human, proof-of-concept, and a broad range of Phase I clinical pharmacology studies. With over 30 years’ experience leading early phase research sites, he is utilized as a global resource within CenExel, providing support to ensure consistency and quality across sites. Dr. Ereshefsky is actively involved in strategic planning for compound development. He helps design translational research programs and define the critical path towards regulatory approval. He has extensive experience working with regulatory agencies and developing strategic plans to address compound differentiation and reimbursement challenges.

Diana Shuster, PhD

Diana Shuster, PhD

Vice President of Clinical Sciences

Diana Shuster, PhD

Dr. Diana Shuster, PhD, serves as Vice President of Clinical Sciences at CenExel, bringing over a decade of expertise in Translational and Early Phase central nervous system research. Her role encompasses the design and execution of first-in-human, proof-of-concept, and diverse Phase I clinical pharmacology studies. With a background spanning big pharma, CROs, and TechBio, Dr. Shuster has significantly contributed to advancing rare disease compounds.

In her capacity as Vice President, Dr. Shuster is dedicated to integrating her multifaceted expertise to ensure consistency and quality across global research sites. Actively engaged in strategic planning, she specializes in designing translational research programs and navigating the critical path to regulatory approval. Driven by a commitment to de-risking early phase drug development, she employs innovative strategies, including continuous CSF sampling, QEEG, ERPs, PSG, fMRI, PET, and cognitive paradigms.

Andrew Birschbach

Andrew Birschbach

VP, Corporate Development & Strategic Finance

Andrew Birschbach

Andrew is a strategic finance professional with experience spanning Fortune 10 public companies to growth-stage, private-equity-backed businesses. His experience includes mergers and acquisitions, business development, operational financial modeling, budgeting, and analysis. Most recently, he was a manager of finance at Alignment Healthcare, an innovative, information-enabled Medicare Advantage company where he provided detailed operational modeling, forecast scenario analysis, analysis for new market expansion, and M&A opportunity evaluation. Prior to Alignment, he was a mergers and acquisitions Senior Associate at UnitedHealth Group’s Corporate Development & Strategy Team.

Mark Trimble, SPHR

Mark Trimble, SPHR

VP, Human Resources & Administration

Mark Trimble, SPHR

Mark is a Human Resources Executive with 20+ years of experience in HR operations and management. Throughout his career he has provided leadership and guidance in the conceptualization, implementation, and management of HR strategies, organizations, programs, and policies. Mark has held several corporate HR leadership positions within the HR outsourcing, life sciences, and healthcare industries.

In his most recent role, prior to joining CenExel, Mark held the position of Regional Vice President of HR Operations for Oasis Outsourcing, a global leader in the Professional Employer Organization industry. In this position, Mark drove positive change through day-to-day operational and financial leadership and competitively evolved HR service offerings for clients in the healthcare and manufacturing industries.

As an HR executive with a strong business acumen, Mark has successfully implemented people-based solutions and the HR function to ensure achievement of corporate business goals. As both an HR strategist and hands-on practitioner, Mark’s areas of expertise include culture alignment and change management, employment law and regulatory compliance, compensation planning, team building, business process and policy formation, talent engagement, and HR consulting.

Mark holds a Bachelor of Science degree in Psychology from BYU and is also certified as a Senior Professional in Human Resources (SPHR).

Hollie DeSmet

Hollie DeSmet

VP, Regulatory and Quality Assurance

Hollie DeSmet

Hollie DeSmet serves as the Vice President of Regulatory and Quality Assurance at CenExel. In her role she leverages her knowledge of CFR, ICH GCP, and FDA Guidance to ensure good clinical practice, focusing on safe, ethical, and high-quality research across CenExel sites.

Hollie joined the Cenexel team from the first site acquired where she held the position of Director of Quality and Compliance. She has a deep familiarity with all CenExel sites and enjoys collaborating with key personnel to oversee the development and implementation of CenExel Standard Operating Procedures, including consistent training practices, quality assurance procedures, and best regulatory practices. She firmly believes that communication is the key to consistency and consistency is the key to quality. Hollie has a passion for swift regulatory processing to ensure a fast-paced study start-up and producing the highest quality data possible for successful study execution.

David Chia

David Chia

Chief Information Officer

David Chia

David Chia oversees IT strategy, implementation, and operations at CenExel – as well as driving the adoption of new technologies, information security, data analytics, and system industry compliance.

David is a 26-year technology leader experienced in IT consulting, development, analytics, and operations. Over the last 13 years he has worked in progressive leadership roles at HCA Healthcare, overseeing IT hospital operations and division application development for 19 hospitals and physician practices over 5 western states. He has received several accolades for his efforts including Innovator of the Year for development of several IT applications and data tools.

David is a graduate of Brigham Young University with degrees in MIS and an MBA. His passion, execution and servant leadership drive him to partner across CenExel to improve the delivery of studies and care through innovation and technology.

Strength in Numbers

Our research-only clinical sites have the medical expertise, resources and established recruitment channels to help go from first-patient-in to last-patient-out faster.
Over

clinical trials conducted successfully.

enrolled patients.
Access to

people in diverse US metro areas.

totally 360,000+ square feet and 600+ beds.
Currently managing

trials and supporting 100+ common indications.
Delivering

%

of patient
recruitment target.
The world's most results-driven life science companies trust our 18 science-led Centers of Excellence to deliver the right patients, at the right time, in the right place.
CenExel combines science, therapeutic insights, clinical expertise, and operational excellence to help guide you from research breakthroughs to transformative patient solutions.